Table 3.
Endometriotic lesions and adhesions 6 months after discontinuation of simvastatin.
| Variable | Control N = 4 | Simvastatin N = 4 | P-value |
|---|---|---|---|
| Number of all lesions | 16.6 ± 4.3 | 11.5 ± 5.2 | 0.51 |
| Combined number of red, orange-red, and white | 10.0 ± 4.2 | 7.3 ± 3.5 | 0.64 |
| Number of red lesions | 1.0 ± 0.4 | 1.8 ± 1.8 | 0.69 |
| Number of orange-red lesions | 0 ± 0.0 | 0.3 ± 0.3 | 0.45 |
| Number of white lesions | 9.0 ± 4.1 | 5.3 ± 2.2 | 0.46 |
| Number of black lesions | 6.3 ± 1.1 | 4.3 ± 2.4 | 0.48 |
| Volume of all lesions (mm3) | 64.3 ± 28.1 | 47.9 ± 20.2 | 0.65 |
| Combined volume of red, orange-red, and white lesions (mm3) | 29.9 ± 20.2 | 35.3 ± 17.5 | 0.85 |
| Volume of red lesions (mm3) | 0.6 ± 0.3 | 1.6 ± 1.6 | 0.55 |
| Volume of orange-red lesions (mm3) | 0 ± 0.0 | 0.02 ± 0.02 | 0.36 |
| Volume of white lesions (mm3) | 29.3 ± 20.3 | 33.7 ± 16.9 | 0.87 |
| Volume of black lesions (mm3) | 34.4 ± 28.9 | 12.6 ± 4.6 | 0.48 |
| Number of adhesions | 4.0 ± 1.2 | 3.0 ± 0.7 | 0.51 |
| Number of filmy adhesions | 1.0 ± 0.4 | 0.8 ± 0.5 | 0.70 |
| Number of dense adhesions | 3.0 ± 1.1 | 2.3 ± 0.5 | 0.55 |
| All adhesions (surface area, mm2) | 356 ± 186 | 191 ± 86 | 0.45 |
| All adhesions (length, mm) | 38.3 ± 17.4 | 30.1 ± 7.3 | 0.70 |
Each value represents mean ± SEM per animal; comparison between groups were performed using the Student t-test or the Wilcoxon test.