. 2018 May 3;39(7):879–888. doi: 10.1093/carcin/bgy062

Table 3.

Combined analysis of the four independent and significant SNPs in four risk groups

Number of risk alleles^a	Frequency		Multivariate analysis^b		AIC^c
Number of risk alleles^a	All	Deaths (%)	HR (95% CI)	P	AIC^c
1–2	46	2 (4.3)^d	1.00
3	158	19 (12.0)	4.81 (1.10–21.00)	0.037
4–5	709	138 (19.5)	8.35 (2.04–34.19)	0.003
6–8	213	53 (24.9)	11.80 (2.84–49.04)	0.001
Trend				5.30E−07	2666.68

AIC, Akaike information criterion.

^aRisk alleles were rs9666607 A, rs35605 C, rs212091 T and rs1058587 G.

^bMultivariate Cox regression analyses were adjusted for age, Gleason score, stage and primary treatments.

^cAIC in the trend model of multivariate Cox regression analyses.

^dTwo patients reached the end point were both with two risk alleles.