. 2017 Nov 14;29(2):466–471. doi: 10.1093/annonc/mdx736

Table 1.

Clinicopathologic characteristics of inverted sinonasal (Schneiderian) papillomas, stratified by EGFR mutation and HPV infection status

Clinicopathologic parameter		EGFR^mut/HPV^neg (n = 53)	EGFR^wt/HPV^pos (n = 5)	P-value
Age at initial diagnosis (years)	Mean	50.8	46.2	0.515
	Median	50	47
	Min	26	24
	Max	84	62
Gender	Female	9 (17.0%)	2 (40.0%)	0.209
Gender	Male	44 (83.0%)	3 (60.0%)
Smoking history	Current/Former	33 (62.3%)	4 (80.0%)	0.678
	Never	19 (35.8%)	1 (20.0%)
	Unknown	1 (1.9%)	0 (0.0%)
Associated sinonasal squamous cell carcinoma	Yes	11 (20.8%)	3 (60.0%)	0.050
Associated sinonasal squamous cell carcinoma	No	42 (79.2%)	2 (40.0%)
Human papillomavirus (HPV) status	Positive	0 (0.0%)	5 (100.0%)	<0.0001
Human papillomavirus (HPV) status	Negative	53 (100.0%)	0 (0.0%)

Mut, mutant; wt, wild-type; pos, positive; neg, negative. Statistically significant P-value in bold.