PrEP trials
Inclusion	Exclusion
•Randomised controlled trials, with a placebo or comparison arm •Published in a peer-reviewed journal •Clinical trials that assess safety of the treatment drug and report absolute numbers of adverse events occurring in both arms	•Non human trials •Earlier than Phase III •Trials of non-oral PrEP (e.g. microbicides) •Substudies looking at the wrong outcome (e.g. measures of adherence and dosing, and measures of qualitative wellbeing or commitment, etc)