Table 1.
Demographics, symptoms, signs and outcomes of suspected Lassa fever in 10 adolescents
| ID | Age/sex | Alive | Positive RT-PCR for LF virus | Presence of symptoms, signs and laboratory abnormalities | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Fever | Prostration | Headache | GI | Renal | Other symptoms/signs | Urine leukocytes | Other labs | ||||
| 1 | 17/m | Yes | Yes | Yes | Yes | Yes | No | No | Conjunctivitis | No | |
| 2 | 14/f | Yes | Yes | Yes | No | Yes | Yes (abdominal pain, vomiting, tenderness) | Yes (dysuria, CVTA) | None | Yes | Proteus spp in the urine, positive malaria parasite, PCV 35% |
| 3 | 14/f | Yes | No | Yes | Yes | Yes | Yes (abdominal pain, tenderness) | No | Conjunctivitis, tachypnoea, tachycardia | Yes | Positive malaria parasite and PCV 32% |
| 4 | 12/f | Yes | No | Yes | Yes | No | Yes (abdominal pain, tenderness) | Yes (dysuria, CVTA) | None | No | |
| 5 | 12/f | Yes | No | Yes | Yes | Yes | Yes (abdominal pain, tenderness) | No | Bleeding, conjunctivitis | No | |
| 6 | 13/f | Yes | Yes | Yes | Yes | No | Yes (abdominal pain, diarrhoea) | Yes(dysuria, CVTA) | None | Yes | PCV 29% |
| 7 | 15/f | Yes | Yes | Yes | Yes | Yes | Yes (abdominal pain, vomiting and tenderness) | Yes (dysuria, CVTA) | Neck stiffness | Yes | |
| 8 | 16/F | Yes | Yes | Yes | Yes | No | Yes (abdominal pain, vomiting, diarrhoea, tenderness) | Yes (CVTA) | Tachypnoea, tachycardia, hypotension, hepatosplenomegaly, with ileal perforation | No | PCV 27% |
| 9 | 16/f | No | Yes | Yes | Yes | Yes | Yes (abdominal pain, vomiting, diarrhoea, tenderness) | Yes (dysuria and CVTA) | Tachypnoea, tachycardia, conjunctivitis, bleeding from all orifices | Yes | |
| 10 | 15/m | Yes | No | Yes | Yes | Yes | Yes (vomiting, diarrhoea, abdominal tenderness) | Yes (CVTA) | Tachycardia | Proteus spp in the urine | |
| Overall (% with signs and symptoms) | Median 14.4 years | 90% | 60% | 100% | 90% | 70% | 90% | 70% | 70% | 60% | 40% |
CVTA: costovertebral angle tenderness; PCV: packed cell volume