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. 2018 May 8;67(3):341–349. doi: 10.1093/cid/ciy088

Table 5.

Conversion of Medically Attended Case Fatality Ratio (CFR) to CFR for All Infected Persons Estimates Using 2 UK Studies

Source Measure Parameter Estimate Lower Bound Upper Bound
This study CFR based on persons with medically attended ILI CFRMA 0.4% 0.2% 0.6%
Brooks-Pollock et al [28]; UK survey of healthcare-seeking behavior in adults Probability of seeking medical care given ILI P(ILIMA|ILI) 0.25 0.25 0.25
Hayward et al [29]; serology study Probability of having ILI symptoms given H1N1pdm infection (based on antibody titers) P(ILI|Inf) 0.25 0.25 0.25
Multiplying the 3 figures CFR based on persons with influenza infection CFRAR 0.03% 0.01% 0.04%

Abbreviations: AR, attack rate; CFR, case fatality ratio; ILI, influenza-like illness; MA, medically attended.