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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Cell Rep. 2016 Nov 8;17(7):1807–1818. doi: 10.1016/j.celrep.2016.10.044

Figure 4. Mutation of SK3 in AgRP/NPY Neurons Increased Susceptibility to DIO.

Figure 4.

(A) Body weight gain of male control and AgRP-SK3-KO littermates since they were switched to HFD feeding. n = 7 or 9 mice per group. Results are shown as mean ± SEM. *p < 0.05 (t tests for each time point).

(B) Cumulative HFD intake. n = 7 or 9 mice per group. Results are shown as mean ± SEM. *p < 0.05 or **p < 0.01 (t tests for each time point).

(C) Fat mass and lean mass gain since HFD feeding. n = 7 or 11 mice per group. Results are shown as mean ± SEM. *p < 0.05 (t tests for each time point).

(D–F) Weights of iWAT (D), gWAT (E) and BAT (F) pads measured at the end of HFD feeding. n = 7 or 9 mice per group. Results are shown as mean ± SEM. *p < 0.05 (t tests).

(G) Relative mRNA levels of indicated genes in BAT. n = 7 mice per group. Results are shown as mean ± SEM. *p < 0.05 (t tests).