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Arginine-rich peptides for bicyclization and control sequences
| Peptide | Sequence[a] | Cyclic form |
|---|---|---|
| 1 | ZCRRRRRRCRRRRRRC |
1b - Trithiol bicycle 1nfb – Non-fluorinated bicycle |
| 2 | ZCRRRCRRRC | 2b - Trithiol bicycle |
| 3 | ZCRRRRRRCCRRRRRRC | 3b - Double macrocycle |
| 4 | ZRRRRRRCCRRRRRR | 4c - Monocycle |
| 5 | ZRRRRRRRRRRRR | None |
| 6 | ZCRRRRRRRRRRRRC | 6c - Monocycle |
| 7 | XKRrRrRrRrRrE | 7c - Lactam monocycle |
Z = 4-pentynoyl, X = 5-azidopentyl; all peptides are C-terminal amides
