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. 2018 Nov 21;13(11):e0206296. doi: 10.1371/journal.pone.0206296

Table 2. Main characteristics of included studies.

Author/Year and Country Evaluation criteria Operators -Training Examiners—blinding Follow-up Drop-out (%) Success rate or Caries lesion arrestment (%)
Louw et al., 2002 (South Africa) ART criteria 5 trained dentists—n/m 2 —n/m 1 year 19.9 ART (HVGIC and Compomer)
HVGIC
(O): 96
(OP): 73
Compomer:
(O): 98
(OP): 78
CRT (HVGIC e Compomer)
HVGIC
(O): 94
(OP): 78
Compomer:
(O): 98
(OP): 79
Taifour et al., 2002 (Syria) ART criteria 8 dentists—three days of training 3 —n/m 3 years 22.1 ART (HVGIC)
(O): 86.1
(OP): 48.7
CRT (AM)
(O): 79.6
(OP): 42.9
Honkala et al., 2003 (Kuwait) ART criteria and USPHS 2 dentists—training with expert 2 –blinding not possible 1 year
2 years
17 ART (HVGIC)
1 year
(O): 100
(OP): 100
2 years
(O): 92.3
(OP): 88.9
CRT (AM)
1 year
(O): 100
(OP): 100
2 years
(O): 92
(OP): 100
Yu et al., 2004 (China) ART criteria 2 experienced dentists—n/m 2 —n/m 6 months
1 year
2 years
42 ART (HVGIC)
6 months
(O): 100
(OP): 82.8
1 year
(O): 94.3
(OP): 65.3
2 years
(O): 91.4
(OP): 52
CRT (AM)
6 months
(O): 100
1 year
(O): 100
2 years
(O): 88.9
CRT (HVGIC)
6 months
(O): 97.8
(OP): 100
1 year
(O): 89.8
(OP): 100
2 years
(O): 89.8
(OP): 84.6
van den Dungen et al., 2004 (Indonesia) ART criteria 2 dentists and 2 undergraduation student—trained for 1 week 10 trained and calibrated undergraduation students—blind 3 years 41.7 ART (HVGIC)
31.0
CRT (HVGIC)
33.6
Roberts et al., 2005 (United Kingdom) In according to the dentist’s assessment 1 dentist—n/m 1 –not blind (same operator) Until 7 years 10.2 CRT (RMGIC)
97.3
SSC
97.0
Ersin et al., 2006 (Turkey) USPHS Ryge criteria 3 dentists—n/m 2 trained and calibrated—blind 6 months
1 year
2 years
17.8 ART (HVGIC)
6 months
(O): 100
(OP): 90.2
1 year
(O): 100
(OP): 83.1
2 years
(O): 96.7
(OP): 76.1
CRT (RC)
6 months
(O): 100
(OP): 92.3
1 year
(O): 98
(OP): 87.5
2 years
(O): 91
(OP): 82
Innes et al., 2011 (Scotland) Innes et al., (2007) criteria 17 trained dentists—n/m 17 dentists—not blind (same operator) Until 5 years 31 CRT (Usual treatment)
52
HT
92
Mijan et al., 2014 (Brazil) PUFA index 3 trained pediatric dentists—n/m 2 trained and calibrated pediatric dentists—n/m 6 months
1 year
2 years
3 years
3.5 years
12.2 ART (HVGIC)
6 months
(OP): 100
1 year
(OP): 97.7
2 years
(OP): 93.1
3 years
(OP): 93.4
3.5 years
(OP): 88.0
CRT (AM)
6 months
(OP): 99.2
1 year
(OP): 96.9
2 years
(OP): 92.4
3 years
(OP): 91.2
3.5 years
(OP): 89.0
UCT
6 months
(OP): 100
1 year
(OP): 95.7
2 years
(OP): 88.0
3 years
(OP): 88.0
3.5 years
(OP): 88.0
Santamaria et al., 2014 (Germany) Innes et al., (2007) criteria 12 trained dentists—n/m 2 trained experienced pediatric dentists—n/m 1 year 12.4 CRT (Compomer)
71
HT
98
NRCT
75
Borges et al., 2012 (Brazil) Criteria reported by Aguilar et al., (2007) 1 trained and experienced dentists—n/m 1 experienced and calibrated—n/m 1 year 13.3 Sealing (RS)
91.6
CRT (RC)
100
Hesse et al., 2014 (Brazil) Criteria reported by Houpt et al., (1983) 1 trained undergraduation student– 1 week of training in patients 1 trained—n/m 6 months
1 year
1.5 years
5.6 Sealing (RS)
6 months: 87.5
1 year: 75.0
1.5 years: 64.7
CRT (RC)
6 months: 100
1 year: 100
1.5 years: 100
Santos et al., 2012 (Brazil) Based on Miller (1959) and Kidd (2010) 1 trained dentist—n/m 1—blinding not possible 6 months
1 year
6.7 IRT (HVGIC)
6 months: 53.1
1 year: 38.6
SDF (30%)
6 months: 84.7
1 year: 66.9
Zhi et al., 2012 (China) Visual and tactile characteristics of caries lesion arrestment 2 trained dentists—n/m 1—blind 6 months
1 year
1.55 years
2 years
15 SDF 1x (38%)
6 months: 31.5
1 year: 37.0
1.5 years: 77.2
2 years: 79.2
SDF 2x (38%)
6 months: 43.3
1 year: 53.0
1.5 years: 82.9
2 years: 90.7
LVGIC
6 months: 31.3
1 years: 28.6
1.5 years: 73.1
2 years: 81.8
Duangthip et al., 2016 (China) Visual and tactile characteristics of caries lesion arrestment 1 dentist—n/m 1—blind 6 months
1 year
1.5 years
9.0 SDF 1x (30%)
6 months: 18
1 year: 20
1.5 years: 40
SDF 3x (30%)
6 months: 31
1 year: 28
1.5 years: 35
NaF 5%
6 months: 10
1 year: 13
1.5 years: 27

Abbreviations: RCT: Randomized Clinical Trial; OP: occlusoproximal; O: occlusal; ART: Atraumatic restorative treatment; CRT: Conventional restorative treatment; SSC: Stainless steel crown; NRCT: Nonrestorative caries treatment; UCT: Ultraconservative treatment; HT: Hall technique; IRT: Interim restorative treatment; SDF: Silver diamine fluoride; LVGIC: Low-viscosity glass ionomer cement; NaF: Sodium fluoride; RS: resin sealant; HVGIC: High-viscosity glass ionomer cement; RC: Resin composite; AM: Amalgam; RMGIC: Resin-modified glass ionomer cement; USPHS: US Public Health Service criteria; PUFA: Index of clinical consequences of untreated dental caries; n/m: Not mentioned.