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. Author manuscript; available in PMC: 2018 Nov 21.
Published in final edited form as: Obes Control Ther. 2017 Dec 18;4(3):10.15226/2374-8354/4/2/00140.

Figure 3: Fermentation of indigestible polysaccharides in colon and production of SCFA, that can further impact diverse mechanisms to maintain human health.

Figure 3:

SCFA i.e. acetate, propionate and butyrate as fermented end products of oligosaccharides contributes in lipid biosynthesis, gluconeogenesis and en-ergy source for colonocytes. In addition, SCFA are also known impact several biological pathways in the host i.e. hormones, eCB system, cell prolifera-tion, cell death, bone health, mineral absorption, gut motility, intestinal pH and back to impact gut microbiome composition and its metabolic function, all these system manipulations contribute in changing metabolic health and energy homeostasis of the host.