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. Author manuscript; available in PMC: 2019 Aug 13.
Published in final edited form as: Biomacromolecules. 2018 Jul 23;19(8):3361–3370. doi: 10.1021/acs.biomac.8b00640

Figure 2. Spherical PP1 micelle characterization.

Figure 2.

Stable, spherical micelles of approximately 50 nm in size were formulated using PP1 polymer. (A) Critical micelle concentration (CMC) measured by pyrene sensitivity assay, (B) TEM images of both sBM and sVPM pre- and post-lyophilization (scale bar = 100 nm), (C) DLS mean size and PDI of both (sBM) and (sVPM) (n=3, mean ± SD, Student’s t-test), (D) zeta potential of sBM and sVPM measured with Zetasizer, and (E) stability of sBM and sVPM in 1x PBS and human serum (45% serum, 55% 1X PBS) at room temperature for 31 hours (n=3, mean ± SD, One-way ANOVA with Dunnett post-hoc test comparing size measurement at different timepoints for each sample to its initial size at t = 0 h).