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. Author manuscript; available in PMC: 2019 Aug 13.
Published in final edited form as: Biomacromolecules. 2018 Jul 23;19(8):3361–3370. doi: 10.1021/acs.biomac.8b00640

Figure 5. Cancer cell uptake.

Figure 5.

VP-loaded micelles are efficiently taken up by two cancer cell types in dose-dependent manner. (A/C) Percentage of cells that internalize VP in human triple-negative breast cancer (MDA-MB 231) and human small cell lung cancer (H446) cells incubated with free VP, sVPM, and fVPM at equivalent VP concentrations from 2.5–20 μM for 1.5 hr and (B/D) the corresponding geometric mean fluorescence of cellular uptake normalized to the untreated condition (RFU) (n=4, mean ± SD, One-way ANOVA with Tukey post-hoc test).