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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Curr Genet. 2017 Aug 2;64(1):87–96. doi: 10.1007/s00294-017-0727-2

Figure 3. Cdc5 localization during the cell cycle.

Figure 3.

Cdc5 starts to accumulate at the SPB in S-phase. Following SPB duplication, in G2, Cdc5 accumulates in the nucleus and decorates the nuclear surface of SPBs. Cdc5 remains in the nucleus and at both SPBs in early anaphase. Later in anaphase, Cdc5 is released from the nucleus to the cytoplasm. In late anaphase, Cdc5 localizes strongly at the cytoplasmic side of the daughter SPB, and weakly at the mother SPB, as well as at the bud neck. After cytokinesis is complete, Cdc5 gets targeted by APCCdh1 for degradation in G1 of the following cell cycle.