Table 1.

Stage	Study
	NWTS-5	NWTS-4
	NWTS-5 definition	NWTS-4 definition	NWTS-5 definition
I	12 (11%)	25 (37%)	17 (25%)
II	44 (41%)	17 (25%)	25 (37%)
III	45 (42%)	24 (35%)	24 (35%)
IV	7 (6%)	2 (3%)	2 (3%)
Total	108	68	68
Five-year EFS	79% (71%−88%)	72% (61%−83%)
Five-year OS	90% (84%−96%)	87% (78%−95%)
Five-year EFS and 95% CI by stage
I	100%(100%−100%)	76% (60%−93%)	82% (64%−100%)
II	88% (77%−99%)	71% (49%−92%)	68% (50%−86%)
I/II	91% (82%−99%)	74% (61%−87%)	74% (61%−87%)
III	73% (59%−87%)	71% (51%−90%)	71% (51%−90%)
IV	29% (0%−76%)	50% (0%−100%)	50% (0%−100%)
III/IV	67% (53%−81%)	69% (50%−88%)	69% (50%−89%)
Five-year OS and 95% CI by stage
I	100% (100%−100%)	92% (81%−100%)	100%(100%−100%)
II	98% (92%−100%)	82% (64%−100%)	80% (64%−96%)
I/II	98% (94%−100%)	88% (78%−98%)	88% (78%−98%)
III	89% (79%−99%)	87% (73%−100%)	87% (73%−100%)
IV	36% (0%−75%)	50% (0%−100%)	50% (0%−100%)
III/IV	82% (71%−93%)	84% (70%−99%)	84% (70%−99%)

EFS – Event-free survival; OS – Overall survival