Table 4.
Total N | Home-based Self-Collection |
Clinic Self-Collection | Clinician Collection | ||||
---|---|---|---|---|---|---|---|
hrHPV%* | (95%CI) | hrHPV% | (95%CI) | hrHPV% | (95%CI) | ||
Cytology (n=193)† | |||||||
Normal | 178 | 8.4 | (5.2–13.4) | 12.4 | (8.3–18.0) | 7.3 | (4.3–12.1) |
ASC-US‡ | 6 | 33.3 | (9.7–70.0) | 16.7 | (3.0–56.4) | 33.3 | (9.7–70.0) |
LSIL§ | 3 | 66.7 | (20.8–93.9) | 66.7 | (20.8–93.9) | 66.7 | (20.8–93.9) |
ASC-H || | 3 | 66.7 | (20.8–93.9) | 66.7 | (20.8–93.9) | 66.7 | (20.8–93.9) |
HSIL+ ¶ | 3 | 100.0 | (43.9–100.0) | 100.0 | (43.9–100.0) | 100.0 | (43.9–100.0) |
Histology (n=190)# | |||||||
Normal** | 184 | 8.7 | (5.4–13.7) | 12.5 | (8.5–18.1) | 7.6 | (4.6–12.4) |
CIN2+†† | 6 | 100.0 | (61.0–100.0) | 83.3 | (43.7–97.0) | 100.0 | (61.0–100.0) |
hrHPV=high-risk human papillomavirus;
Analyses limited to participants with conclusive cytology and hrHPV results on all three sample types;
ASC-US=atypical squamous cells of undetermined significance;
LSIL=low-grade squamous intraepithelial lesion;
ASC-H=atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion;
HSIL+=high-grade squamous intraepithelial lesion or worse;
Excludes 1 ASC-US hrHPV-positive, 1 ASC-H, and 1 LSIL referred to colposcopy but lost to follow-up. No CIN1 cases were detected.
Includes women with normal cytology for whom colposcopy was not recommended and thus histology not conducted.
CIN2+=cervical intraepithelial neoplasia 2 or more severe; Histology results: 3 cases CIN2/3, 2 cases CIN3, 1 case CIN3/CIS