Table 4:
Association Between Patient/Demographic Characteristics and Enrollment on a Clinical Trial, Multivariable Logistic Regression, Stratified by Year of Diagnosis, National Cancer Institute Patterns of Care Study (N=3,135)+
| Characteristic | Year of Diagnosis, 2006 | Year of Diagnosis, 2012-2013 | ||
|---|---|---|---|---|
| Patient | ||||
| Odds Ratio | 95% CI | Odds Ratio | 95% CI | |
| Cancer Type | ||||
| Non-Hodgkin Lymphoma | Ref. | Ref. | ||
| Hodgkin Lymphoma | 1.79 | (0.84,3.87) | 1.18 | (0.61,2.26) |
| Acute Lymphoblastic Leukemia | 10.96 | (3.83,31.35) | 13.31 | (4.81,36.81) |
| Sarcoma | 4.55 | (2.03,10.16) | 2.93 | (1.21,7.08) |
| American Joint Commission on Cancer Stage | ||||
| I | Ref. | Ref. | ||
| II | 2.23 | (0.91,5.49) | 1.24 | (0.50,3.08) |
| III | 2.40 | (0.89,6.49) | 1.31 | (0.54,3.19) |
| IV | 2.25 | (0.83,6.12) | 1.43 | (0.67,3.05) |
| 0/Unknown/Unstaged | 0.79 | (0.28,2.22) | 0.58 | (0.21,1.63) |
| Age at Diagnosis, Years | ||||
| 15-19 | Ref. | Ref. | ||
| 20-24 | 0.49 | (0.25,0.96) | 0.69 | (0.42,1.13) |
| 25-29 | 0.21 | (0.08,0.55) | 0.63 | (0.35,1.11) |
| 30-34 | 0.28 | (0.11,0.67) | 0.21 | (0.11,0.42) |
| 35-39 | 0.21 | (0.08,0.54) | 0.32 | (0.17,0.61) |
| Race/Ethnicity | ||||
| Non-Hispanic White | Ref. | Ref. | ||
| Non-Hispanic Black | 0.63 | (0.31,1.29) | 0.66 | (0.41,1.09) |
| Hispanic | 0.89 | (0.47,1.72) | 0.69 | (0.43,1.13) |
| Other* | 0.82 | (0.36,1.87) | 0.55 | (0.32,0.95) |
| Sex | ||||
| Male | Ref. | Ref. | ||
| Female | 0.73 | (0.43,1.24) | 1.07 | (0.72,1.57) |
| Marital Status | ||||
| Married | Ref. | Ref. | ||
| Other | 0.59 | (0.31,1.16) | 0.97 | (0.61,1.56) |
| Comorbidities | ||||
| No | Ref. | Ref. | ||
| Yes | 0.99 | (0.58,1.69) | 0.90 | (0.63,1.30) |
| Insurance | ||||
| Private | Ref. | Ref. | ||
| Public | 0.99 | (0.53,1.88) | 0.91 | (0.59,1.39) |
| No-Insurance/Unknown | 0.29 | (0.10,0.82) | 1.13 | (0.44,2.92) |
| Census Tract Median Family Income ($, Thousands) | ||||
| <55 | 1.56 | (0.73,3.37) | 1.40 | (0.85,2.33) |
| 55-<75 | 0.79 | (0.47,1.32) | 1.04 | (0.68,1.59) |
| >=75 | Ref. | Ref. | ||
| Provider | ||||
| Physician Specialty | ||||
| Pediatric Hematology/Oncology only | Ref. | Ref. | ||
| Adult Hematology/Oncology Only | 0.16 | (0.05,0.49) | 0.36 | (0.10,1.32) |
| Pediatric Hematology/Oncology + Other | 0.54 | (0.18,1.64) | 1.13 | (0.31,4.10) |
| Adult Hematology/Oncology +Other/Unknown | 0.14 | (0.05,0.42) | 0.18 | (0.05,0.65) |
| Treating Hospital Bed Size | ||||
| <200 | Ref. | Ref. | ||
| 200-299 | 1.66 | (0.60,4.60) | 0.79 | (0.43,1.46) |
| 300-399 | 2.60 | (1.09,6.19) | 1.43 | (0.73,2.81) |
| >=400 | 2.09 | (0.89,4.90) | 1.00 | (0.61,1.66) |
| Unknown + Outpatient/Physician Office | 3.50 | (0.90,13.63) | 0.70 | (0.21,2.31) |
| Residency Training Program | ||||
| Yes | Ref. | Ref. | ||
| No/Unknown | 0.90 | (0.47,1.73) | 0.57 | (0.33,0.98) |
*
Includes Asian/Pacific Islander; American Indian/Alaskan Native; Bold indicated P<0.05
+
Multivariable models include all patient and provider characteristics listed.