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. Author manuscript; available in PMC: 2020 Mar 8.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 28;89:57–64. doi: 10.1016/j.pnpbp.2018.08.017

Figure 1: Regulatory genes disrupted in ASD.

Figure 1:

High confidence ASD genes regulate multiple levels of gene expression. CHD8 (purple) is a chromatin remodeler and is associated with open chromatin and active promoters. FOXP1 is a transcriptional factor (green) active or repress its transcriptional targets. RBFOX1 (red) is a RNA binding protein and regulates RNA metabolism including splicing.