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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Arthritis Care Res (Hoboken). 2019 Feb;71(2):308–318. doi: 10.1002/acr.23601

Table 2.

Brain regions showing significant rCBF changes in response to the stimuli.

Group Contrast Cluster size (# voxels) Cluster P-value Local maxima
Z x (mm) y (mm) z (mm) Label
RA low stimulus > baseline 3714 0.0023 4.96 22 12 52 R superior frontal sulcus
3.58 10 10 52 R pre-supplementary motor area
3.56 0 2 42 anterior middle cingulate cortex
3.41 −4 4 46 L anterior middle cingulate cortex /pre-supplementary motor area
3.11 32 −12 56 R precentral gyrus
baseline > low stimulus n.s.
high stimulus > baseline 4078 0.00161 3.55 8 48 12 R pregenual anterior cingulate cortex
3.34 10 22 44 R pre-supplementary motor area
3.08 −6 48 12 L pregenual anterior cingulate cortex
3.04 −16 22 46 L superior frontal sulcus
2.7 −10 24 40 L pre-supplementary motor area
baseline > high stimulus n.s.
controls low stimulus > baseline n.s.
baseline > low stimulus 1951 0.0336 3.34 −38 58 14 L frontal pole
3.22 2 58 10 R medial prefrontal cortex
3.04 −30 32 38 L middle frontal gyrus
2.89 10 58 32 R frontal pole
high stimulus > baseline n.s.
baseline > high stimulus n.s.