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. 2018 Nov 21;9:4917. doi: 10.1038/s41467-018-07412-6

Fig. 2.

Fig. 2

The CBAD biosynthetic pathway and LC–MS detection of biosynthetic intermediates. a HBA is converted to CBAD by CobB and the CobN,S,T enzymes. b The strain FH131 expressing cobB converted HBA to HBAD, as assessed by HPLC. c Comparison of mass spectra for HBAD from the FH001 and FH131 stains. d Comparison of mass spectra for CBAD from recombinant E. coli stains with or without the expression of the cbiM,N,Q,O proteins