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. 2018 Nov 21;50(11):154. doi: 10.1038/s12276-018-0177-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a, d A tube formation assay was used to investigate the effect of melatonin on EPC neovascularization. Scale bar, 50 μm. b, e A transwell migration assay was used to study the effects of melatonin on EPC migration. Scale bar, 50 μm. c, f An adhesion assay was performed to determine the effects of melatonin on adhesion in EPCs. Scale bar, 100 μm. Data are presented as the mean ± SEM. Significant differences between the treatment and control groups are indicated as **P < 0.01 or *P < 0.05. n = 3