Fig. 1.

Overview of data. a Illustration of the matched case-control cohort. Prostate tumor samples from 49 patients with biochemical recurrence were matched to 50 patients without a recurrence. Samples were matched on clinical parameters age, TNM stage, PSA level, and Gleason score. Fresh frozen material of each patient was processed for RNA-seq, AR ChIP-seq, H3K27ac ChIP-seq, H3K4me3 ChIP-seq, and H3K27me3 ChIP-seq. The male silhouette was adapted from Wikipedia (https://upload.wikimedia.org/wikipedia/commons/archive/4/4e/20180727161732%21Aiga_toiletsq_men.svg). b Data availability for RNA-seq, AR ChIP-seq, H3K27ac ChIP-seq, H3K4me3 ChIP-seq, and H3K27me3 ChIP-seq for each sample. Columns represent individual patient samples. Cases and controls are depicted in red and blue, respectively. Two samples without follow-up are depicted in green (top row)