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. 2018 Nov 21;8:17171. doi: 10.1038/s41598-018-35649-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Patterns of neuronal response to PFC stimulation. Single neurons were recorded throughout the BLA. Three types of responses were characterized based on criteria (Methods). Shown in all the examples here are 50 consecutive overlaid traces of the response to stimulation (top), the peristimulus time histograms (middle) and overlaid traces of the responses at a smaller time scale (bottom). Stimulation occurred at the arrowheads. (A) Example of a neuron that displayed excitation in response to PFC stimulation. (B) Example of a neuron that displayed inhibition in response to PFC stimulation. (C) Example of a neuron that displayed no response to PFC stimulation. Stimulation artifacts were blanked for clarity.