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. 2018 Nov 15;9:1276. doi: 10.3389/fphar.2018.01276

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Copyright © 2018 Shi, Chen, Xie, Yang, Liu, Dai and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of inflammation- and oxidative stress-related factors. (A) IL-8 levels in mouse serum and bronchoalveolar lavage fluid (BALF). (B) TNF-a levels in mouse serum and bronchoalveolar lavage fluid (BALF). (C) MCP-1 levels in mouse serum and BALF. (D) MCP-1 levels in the supernatant of Beas-2B cells. (E) SOD levels in mouse serum and BALF. (F) CAT levels in mouse serum and BALF. (G) SOD levels in the supernatant of Beas-2B cells. (H) CAT levels in the supernatant of Beas-2B cells. Each result was derived from three independent experiments. Control group were treated with DMSO; CSE group were treated with CSE and DMSO; CSE + celastrol were treated with CSE and celastrol. Values are expressed as the mean ± SEM (n = 3); ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 with respect to the control group; ^#p < 0.05, ^##p < 0.01 with respect to the CSE group or COPD group.