Table 5. Adjusted cost difference of the total cost of care and cardiovascular-related cost by lipid goal attainments among 2686 patients with complete five-year follow-up.
Total cost of care (HKD) |
Cardiovascular-related cost (HKD) |
||||||
---|---|---|---|---|---|---|---|
N | Adjusted Coefficient* | (95% Confidence Interval) | p-value | Adjusted Coefficient* | (95% Confidence Interval) | p-value | |
Endpoint LDL-C achieving the goal of 2.6 mmol/L | 2686 | ||||||
1st year: At goal vs Not at goal | 2686 | 6548.52 | (−3441.94, 16538.97) | 0.20 | 10495.13 | (5846.36, 15143.89) | < 0.001 |
2nd year: At goal vs Not at goal | 2686 | 1433.02 | (−6835.65, 9701.69) | 0.73 | −1637.26 | (−5892.56, 2618.05) | 0.45 |
3rd year: At goal vs Not at goal | 2686 | 1404.19 | (−6251.35, 9059.74) | 0.72 | −7.59 | (−3437.71, 3422.53) | 1.00 |
4th year: At goal vs Not at goal | 2686 | −4251.30 | (−11714.31, 3211.71) | 0.26 | −1776.81 | (−5662.26, 2108.64) | 0.37 |
5th year: At goal vs Not at goal | 2686 | −748.84 | (−7558.02, 6060.34) | 0.83 | −1529.18 | (−5146.36, 2088.00) | 0.41 |
Endpoint LDL-C achieving the goal of 1.8 mmol/L | 2686 | ||||||
1st year: At goal vs Not at goal | 2686 | 12764.70 | (1199.33, 24330.08) | 0.03 | 8367.48 | (1343.69, 15391.27) | 0.02 |
2nd year: At goal vs Not at goal | 2686 | 10694.72 | (1936.13, 19453.32) | 0.02 | 739.51 | (−2118.36, 3597.39) | 0.61 |
3rd year: At goal vs Not at goal | 2686 | 4185.83 | (−3570.15, 11941.81) | 0.29 | 2323.03 | (−1117.32, 5763.37) | 0.19 |
4th year: At goal vs Not at goal | 2686 | −2747.02 | (−9003.42, 3509.38) | 0.39 | −1263.53 | (−4107.77, 1580.71) | 0.38 |
5th year: At goal vs Not at goal | 2686 | 367.42 | (−6025.01, 6759.85) | 0.91 | 21.21 | (−2939.33, 2981.74) | 0.99 |
Endpoint LDL-C achieving the goal of 2.0 mmol/L | 2686 | ||||||
1st year: At goal vs Not at goal | 2686 | 8031.90 | (−2052.35, 18116.14) | 0.12 | 7683.58 | (1678.83, 13688.32) | 0.01 |
2nd year: At goal vs Not at goal | 2686 | 6080.24 | (−1372.17, 13532.65) | 0.11 | −167.99 | (−2973.12, 2637.14) | 0.91 |
3rd year: At goal vs Not at goal | 2686 | 1853.03 | (−5091.22, 8797.29) | 0.60 | 1056.23 | (−1890.38, 4002.83) | 0.48 |
4th year: At goal vs Not at goal | 2686 | −6025.85 | (−11884.44, −167.25) | 0.04 | −2474.41 | (−5301.74, 352.93) | 0.09 |
5th year: At goal vs Not at goal | 2686 | −405.39 | (−6530.61, 5719.83) | 0.90 | −1076.21 | (−3926.35, 1773.94) | 0.46 |
Endpoint LDL-C achieving the reduction of 50% | 2412 | ||||||
1st year: At goal vs Not at goal | 2412 | 16472.69 | (−2613.22, 35558.59) | 0.09 | 10607.64 | (297.47, 20917.80) | 0.04 |
2nd year: At goal vs Not at goal | 2412 | −3062.50 | (−11721.47, 5596.48) | 0.49 | −1222.43 | (−4448.06, 2003.20) | 0.46 |
3rd year: At goal vs Not at goal | 2412 | −1969.65 | (−13188.12, 9248.82) | 0.73 | −182.27 | (−5121.42, 4756.89) | 0.94 |
4th year: At goal vs Not at goal | 2412 | −4115.05 | (−13228.67, 4998.58) | 0.38 | −2179.64 | (−5794.71, 1435.42) | 0.24 |
5th year: At goal vs Not at goal | 2412 | 2065.28 | (−10846.31, 14976.88) | 0.75 | −1675.69 | (−5453.84, 2102.45) | 0.38 |
MACE, major adverse cardiovascular events; LDL-C, low-density lipoprotein cholesterol; HKD, Hong Kong dollars; Ref, reference.
Adjusted for age, sex, diabetes, hypertension, and prior cardiovascular history