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. 2018 Dec 1;25(12):1255–1273. doi: 10.5551/jat.44818

Table 5. Adjusted cost difference of the total cost of care and cardiovascular-related cost by lipid goal attainments among 2686 patients with complete five-year follow-up.

Total cost of care (HKD)
Cardiovascular-related cost (HKD)
N Adjusted Coefficient* (95% Confidence Interval) p-value Adjusted Coefficient* (95% Confidence Interval) p-value
Endpoint LDL-C achieving the goal of 2.6 mmol/L 2686
    1st year: At goal vs Not at goal 2686 6548.52 (−3441.94, 16538.97) 0.20 10495.13 (5846.36, 15143.89) < 0.001
    2nd year: At goal vs Not at goal 2686 1433.02 (−6835.65, 9701.69) 0.73 −1637.26 (−5892.56, 2618.05) 0.45
    3rd year: At goal vs Not at goal 2686 1404.19 (−6251.35, 9059.74) 0.72 −7.59 (−3437.71, 3422.53) 1.00
    4th year: At goal vs Not at goal 2686 −4251.30 (−11714.31, 3211.71) 0.26 −1776.81 (−5662.26, 2108.64) 0.37
    5th year: At goal vs Not at goal 2686 −748.84 (−7558.02, 6060.34) 0.83 −1529.18 (−5146.36, 2088.00) 0.41
Endpoint LDL-C achieving the goal of 1.8 mmol/L 2686
    1st year: At goal vs Not at goal 2686 12764.70 (1199.33, 24330.08) 0.03 8367.48 (1343.69, 15391.27) 0.02
    2nd year: At goal vs Not at goal 2686 10694.72 (1936.13, 19453.32) 0.02 739.51 (−2118.36, 3597.39) 0.61
    3rd year: At goal vs Not at goal 2686 4185.83 (−3570.15, 11941.81) 0.29 2323.03 (−1117.32, 5763.37) 0.19
    4th year: At goal vs Not at goal 2686 −2747.02 (−9003.42, 3509.38) 0.39 −1263.53 (−4107.77, 1580.71) 0.38
    5th year: At goal vs Not at goal 2686 367.42 (−6025.01, 6759.85) 0.91 21.21 (−2939.33, 2981.74) 0.99
Endpoint LDL-C achieving the goal of 2.0 mmol/L 2686
    1st year: At goal vs Not at goal 2686 8031.90 (−2052.35, 18116.14) 0.12 7683.58 (1678.83, 13688.32) 0.01
    2nd year: At goal vs Not at goal 2686 6080.24 (−1372.17, 13532.65) 0.11 −167.99 (−2973.12, 2637.14) 0.91
    3rd year: At goal vs Not at goal 2686 1853.03 (−5091.22, 8797.29) 0.60 1056.23 (−1890.38, 4002.83) 0.48
    4th year: At goal vs Not at goal 2686 −6025.85 (−11884.44, −167.25) 0.04 −2474.41 (−5301.74, 352.93) 0.09
    5th year: At goal vs Not at goal 2686 −405.39 (−6530.61, 5719.83) 0.90 −1076.21 (−3926.35, 1773.94) 0.46
Endpoint LDL-C achieving the reduction of 50% 2412
    1st year: At goal vs Not at goal 2412 16472.69 (−2613.22, 35558.59) 0.09 10607.64 (297.47, 20917.80) 0.04
    2nd year: At goal vs Not at goal 2412 −3062.50 (−11721.47, 5596.48) 0.49 −1222.43 (−4448.06, 2003.20) 0.46
    3rd year: At goal vs Not at goal 2412 −1969.65 (−13188.12, 9248.82) 0.73 −182.27 (−5121.42, 4756.89) 0.94
    4th year: At goal vs Not at goal 2412 −4115.05 (−13228.67, 4998.58) 0.38 −2179.64 (−5794.71, 1435.42) 0.24
    5th year: At goal vs Not at goal 2412 2065.28 (−10846.31, 14976.88) 0.75 −1675.69 (−5453.84, 2102.45) 0.38

MACE, major adverse cardiovascular events; LDL-C, low-density lipoprotein cholesterol; HKD, Hong Kong dollars; Ref, reference.

*

Adjusted for age, sex, diabetes, hypertension, and prior cardiovascular history