Table 4. Standardized regression coefficient for log-transformed IL-6 by multiple regression analysis (1) grouped by those who worked only night shift and other groups (N = 5259), and (2) including those with a history of myocardial infarction, stroke, depression, and malignant tumor (N = 6407).

	(1)						(2)
	Model 1		Model 2		Model 3		Model 1		Model 2		Model 3
Work schedule	β (SE)	P value	β (SE)	P value	β (SE)	P value	β (SE)	P value	β (SE)	P value	β (SE)	P value
Regular work							Ref		Ref		Ref
Shift work							0.005	0.79	−0.013	0.50	0.002	0.07
without night work							(0.019)		(0.019)		(0.020)
Shift work							0.017	0.83	0.015	0.08	0.001	0.81
with night work							(0.008)		(0.008)		(0.009)
Works other than	Ref		Ref		Ref
only night shift
Only night work	0.077	< 0.001	0.086	< 0.001	0.061	0.005	−0.078	< 0.001	0.089	< 0.001	0.058	0.007
	(0.022)		(0.022)		(0.021)		(0.022)		(0.022)		(0.022)

Model 1: unadjusted

Model 2: includes age, sex

Model 3: includes Model 2, years of education, hours worked per week, annual household income, BMI, laboratory data (LDL-C, HbA1c), job stress

Abbreviations: β, regression coefficients; LDL-C, low-density lipoprotein cholesterol; ref, reference; SE, standard error.