Table 2. Multivariable adjusted hazard ratios for incidence of a high level of non-HDL-C by potential risk factors.

Potential risk factors	Participants	Number of cases	Incidence rate§	Hazard ratio (95% CI)	p value
Age (single year)	4.067	1.482	30.7	1.01 (1.00–1.01)	0.015
Body mass index
1st tertile (Low)	1.362	412	23.4	1.00 (Reference)	−
2nd tertile (Middle)	1.357	498	30.4	1.27 (1.11–1.45)	< 0.001
3rd tertile (High)	1.348	572	39.9	1.58 (1.38–1.80)	< 0.001
Sytolic blood pressure
< 140 mmHg	3.474	1.264	29.9	1.00 (Reference)	−
≥ 140 mmHg	593	218	35.9	1.06 (0.92–1.23)	0.425
Smoking status
None	1.600	592	32.0	1.00 (Reference)	−
1–20 cigarettes/day	1.453	506	28.7	0.96 (0.85–1.09)	0.524
≥ 21 cigarettes/day	1.014	384	31.6	1.02 (0.90–1.16)	0.754
Alcohol intake
None	1.187	440	30.7	1.00 (Reference)	−
1–45 g/day	2.672	971	30.8	0.95 (0.85–1.07)	0.424
≥ 46 g/day	208	71	28.8	0.84 (0.65–1.08)	0.173
Family history of dyslipidemia
No	3.949	1.412	30.1	1.00 (Reference)	−
Yes	118	70	53.3	1.85 (1.45–2.35)	< 0.001

CI, confidence interval

Adjusted for cardiorespiratory fitness level and all items in the table.

^§Incidence rate is presented in cases per 1,000 man-years of observation.