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. 2018 Dec 1;25(12):1240–1254. doi: 10.5551/jat.44297

Fig. 7.

Fig. 7.

Diagram of proposed mechanisms for atherosclerosis

Both M1- and M2-like macrophages are present in atherosclerotic lesions. Their balance is associated with the distribution of VSMC and is regulated by histamine and cytokines that affect atherosclerosis.