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. 2018 Nov 15;9:964. doi: 10.3389/fneur.2018.00964

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Copyright © 2018 Madathil, Wilfred, Urankar, Yang, Leung, Gilsdorf and Shear.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single gene qRT-PCR of selected targets in the ipsilateral cortex. Selected gene targets including both (A) M-1 and (B) M-2 markers are run separately using individual samples (n = 10/condition). RT-1HA was included as this is part of MHC-II complex. One-way ANOVA with Tukey's post-hoc test. ^*p<0.05 compared to single hit 6 h. ^@p < 0.05 compared to repeated hit 6 h. ^#p < 0.05 compared to Single hit 72 h. SC: single concussion, RC: repeated concussion, CX: cortex.