Table 2.

Relative Quantification of Plasma miRNA-21 level (Mean ±SD) among the Study Population

Variables	Plasma miRNA-21 level (Mean ±SD)	95% Confidence interval	p value
Study Population
Lung cancer patients	2.32 ± 1.7	1.95 to 2.69	<0.0001
Healthy controls	0.715 ± 0.48	0.60 to 0.82
	Lung cancer patients (n=80)
Gender
Male	2.15 ±1.49	1.75 to 2.55	0.153
Female	2.75 ±1.98	1.86 to 3.63
TNM Stage
I	3.14 ±0.71	-3.21 to 9.49	0.829
II	2.32 ±1.55	0.89 to 3.76
III	2.13 ±1.77	0.35 to 1.41
IV	2.40 ±1.66	1.89 to 2.89
Distant Metastases
M0	2.21 ±1.68	1.65 to 2.80	0.667
M1	2.4 ±1.66	1.89 to 2.89
Histological type
ADC	2.16 ±1.5	1.77 to 2.56	0.159
SCC	2.77 ±1.98	1.84 to 3.69
Histological Grades
Grade 1	1.15 ±1.26	-10.2 to 12.5	0.333
Grade 2	2.53 ±1.72	1.92 to 3.14
Grade 3	2.09 ±1.55	1.54 to 2.64
Smoking status
Smoker	2.71 ±1.92	1.93 to 3.48	0.147
Non-Smoker	2.13 ±1.49	1.72 to 2.54