Table 2.
Assessment of risk factors for reoperation using Cox regression analysis
| Variable | Reoperation HR (95%CI) | P value | Valve op HR (95% CI) | P value | LVOTO HR (95% CI) | P value |
|---|---|---|---|---|---|---|
| Down | 0.49 (0.17-1.41) | 0.191 | 0.84 (0.21-3.37) | 0.812 | 0.45 (0.11-1.85) | 0.271 |
| Preoperative left AV valve insufficiency | 0.048 | 0.050 | 0.767 | |||
| Minimal | 1 | 0.754 | 1 | 0.801 | 1 | |
| Mild | 1.41 (0.16-12.41) | 0.787 | 0.73 (0.06-7.90) | 0.410 | 0.950 | |
| Moderate | 0.74 (0.08-6.36) | 0.402 | 0.37 (0.03-3.85) | 0.615 | 0.952 | |
| Severe | 2.43 (0.30-19.60) | 1.76 (0.19-16.24) | 0.948 | |||
| Type of AVSD | 0.51 (0.20-1.28) | 0.155 | 0.17 (0.04-0.64) | 0.009 | 0.68 (0.16-2.88) | 0.603 |
| Years of operation | 0.008 | 0.074 | 0.004 | |||
| 1996–2001 | 1 | 0.014 | 1 | 1 | 1 | 0.001 |
| 2002–2007 | 0.21 (0.06-0.72) | 0.003 | 0.68 (0.14-3.28) | 0.635 | 0.002 (0.00-0.09) | 0.054 |
| 2008–2016 | 0.22 (0.08-0.60) | 0.27 (0.76-0.96) | 0.043 | 0.20 (0.04-1.02) | ||
| Associated cardiac anomalies | 1.30 (0.63-2.68) | 0.476 | 1.44 (0.55-3.75) | 0.452 | 1.00 (0.33-3.00) | 0.987 |
| Age | 0.99 (0.95-1.02) | 0.686 | 1.03 (0.99-1.078) | 0.098 | 0.88 (0.81-0.97) | 0.009 |
| Weight | 1.03 (0.89-1.18) | 0.663 | 0.82 (0.65-1.03) | 0.095 | 1.37 (1.07-1.76) | 0.012 |
| Cleft closure | 0.48 (0.10-2.31) | 0.366 | 0.30 (0.03-2.62) | 0.279 | 2.12 (0.18-23.94) | 0.541 |
| Technique | 1.26 (0.59-2.68) | 0.549 | 2.13 (0.50-9.03) | 0.303 | 1.46 (0.60-3.57) | 0.403 |
| Postop left AV valve insufficiency | 1.90 (1.25-2.88) | 0.002 | 3.26 (1.87-5.66) | 0.000 | 0.49 (0.23-1.05) | 0.067 |
AV – atrioventricular, AVSD – atrioventricular septal defect, CI – confidence interval, HR – hazard ratio, LVOTO - left ventricular outflow tract obstruction