Table 3.
Comparison between the groups in terms of laboratory values and endothelial biomarkers
| CVAE (–) | CVAE (+) Mean±SD | Median (min.-max.) | Mean±SD (min.-max.) | Median | P |
|---|---|---|---|---|---|
| *Glucose (mg/dL) | 118.7±45.6 | 104.5 (68-280) | 145.2±79.1 | 114 (61-380) | 0.238 |
| *Creatinine (mg/dL) | 1.1±0.3 | 1 (0.7-2.35) | 1.1±1 | 0.9 (0.1-5.1) | 0.077 |
| Total cholesterol (mg/dL) | 199.7±51.8 | 194.9±46.8 | 0.704 | ||
| HDL (mg/dL) | 44.7±11.1 | 38.4±9.1 | 0.020 | ||
| LDL (mg/dL) | 117.4±41.6 | 116±32.4 | 0.885 | ||
| *VLDL (mg/dL) | 39.1±24.5 | 31.5 (11-109) | 40.5±20.3 | 37 (8-64) | 0.384 |
| *Triglyceride (mg/dL) | 155.1±98.3 | 122 (55-479) | 157±55.8 | 161.5 (71-276) | 0.163 |
| *Total bilirubin (mg/dL) | 0.4±0.1 | 0.4 (0.1-0.9) | 0.6±0.3 | 0.5 (0.1-1.6) | 0.240 |
| *Homocysteine (µmol/L) | 12.4±6.8 | 12.3 (1.2-32) | 11.1±6.9 | 9.8 (1.2-32) | 0.332 |
| *hs-CRP (mg/L) | 5.9±10.9 | 2.9 (0.2-59) | 14.3±20.6 | 6.8 (0.8-90) | 0.004 |
| *WBC (µL) | 9±2.9 | 8.1 (4.9-16.8) | 9.5±3.1 | 8.7 (4.9-16.4) | 0.458 |
| Hemoglobin (g/dL) | 14.1±1.9 | 13.7±2.2 | 0.506 | ||
| Hemoglobin A1c (%) | 6.9±1.4 | 6.3±1.7 | 0.391 | ||
| Uric acid (mg/dL) | 5.8±1.4 | 4.9±1.5 | 0.082 | ||
| NO (µM) | 67.2±30 | 79±41.5 | 0.329 | ||
| TAC (µM) | 733.9±184.9 | 709.9±94.2 | 0.604 | ||
| *ADMA (µM) | 1.2±1.4 | 0.8 (0.1-6.4) | 2.1±3.1 | 0.7 (0.3-10.7) | 0.792 |
| *H2S (µM) | 52.9±35.8 | 41.7 (14.5-164.7) | 48±30.1 | 45.9 (12.1-110.8) | 0.695 |
*
These variables were compared with nonparametric Mann–Whitney U test because they were not normally distributed.
CVAE - cardiovascular adverse events; HDL - high density lipoprotein cholesterol; LDL - low density lipoprotein cholesterol; VLDL - very low density lipoprotein cholesterol; hs-CRP - high-sensitivity C-reactive protein; WBC - white blood cell; NO - nitric oxide; TAC - total antioxidant capacity; ADMA - asymmetric dimethyl arginine; H2S - hydrogen sulfide;