Table 3.
CD-1 survival (n = 6) | ||||
---|---|---|---|---|
Daily treatment | ||||
Mouse age | − | + | ||
Survival | Time to death, days after infection | Survival | Time to death, days after infection | |
6 wk | 0% | 5–7 | 0% | 6–7 |
8 wk | 0% | 5–7 | 0% | 5–7 |
10 wk | 0% | 6–7 | 0% | 6–8 |
12 wk | 0% | 5–8 | 0% | 5–7 |
14 wk | 0% | 6–7 | 0% | 6–7 |
Groups of 6 mice of the noted ages were intraperitoneally infected with 10 focus-forming units of mouse-adapted Ebola virus (1000 lethal dose causing 50% mortality), with or without additional daily intraperitoneal injections of Dulbecco’s modified Eagle medium.