Figure 1.

In vitro antiviral effect of T-705 against Sudan virus (SUDV). Vero E6 cells were pre-treated with a dilution series of T-705 (starting at 100 µg/mL followed by 1:3 dilutions) for 1 hour prior to infection with wild type SUDV at MOI 0.01. After 72 hours post infection, SUDV RNA in the supernatant was measured by reverse transcription–quantitative polymerase chain reaction (RT-qPCR). The half maximal effective concentration (EC₅₀) and 90% effective inhibitory concentration (EC₉₀) values for T-705 were calculated from the sigmoidal function. Abbreviation: CI, confidence interval..