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Mean particle size, polydispersity index (PDI), zeta potential (ζ), Encapsulation Efficiency (EE%) and Loading Capacity (LC%) of different ME-based NLC formulations.
| Code | S:Co-S (w/w ratio) | size (nm) | PDI | ζ (mV) | EE% | LC% |
|---|---|---|---|---|---|---|
| NLCI | Tween®80:Tween®20 | 327.6 ± 3.7 | 0.38 ± 0.03 | −25.1 ± 0.3 | 93.2 ± 0.5 | 3.7 ± 0.2 |
| 1:4 | ||||||
| NLCII | Tween®80:Solutol®HS | 429.3 ± 11.2 | 0.39 ± 0.02 | −25.0 ± 0.9 | 86.0 ± 0.3 | 3.4 ± 0.2 |
| 1:1 | ||||||
| NLCIII | Pluronic®F68:Tween®20 | >1μm | 1 | – | – | – |
| 1:2 | ||||||
| NLCIV | Pluronic®F68:Tween®20 | >1μm | 1 | – | – | – |
| 1:4 |
