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. 2018 Dec;7(6):616–630. doi: 10.21037/tlcr.2018.08.01

Figure 2.

Figure 2

Germ-line filtering and distribution of variants called by TML assay. (A) Allele frequency distribution of all variants before applying germ-line filtering and only somatic variants after applying germ-line filtering from an FFPE tumor; (B) allele frequency distribution of a possible LOH FFPE tumor and matched normal before applying germ-line filtering; (C) allele frequency distribution of variants in individual chromosomes of LOH tumor from B. TML, tumor mutation load; LOH, loss of heterozygosity; FFPE, formalin-fixed, paraffin-embedded.