Table 1.

The Expression of CTGF Pathway Members Was Altered in bLRs in the Dentate Gyrus

Transcript	bLR-VEH vs. bHR-VEH	bLR-FGF2 vs. bLR-VEH
CTGF	Up^a	Down^a
ECM2		Down
EGR1		Down^a
BCL2L2	Up^a	Up^a
IGFBP7	Up	Down^a
P4HA1		Down^a
PDGFβ	Down
MAPKAPK5	Up^a
MAPK8IP3	Up^a
PKN1	Up^a
PRKAG1	Up^a
CREB1		Down
RHOG	Up^a
RHOA	Down^a	Up^a
SOX4		Up^a
STK3		Up^a

BCL2L2, Bcl-2-like protein 2; bHR, bred high responder; bLR, bred low responder; CREB1, cyclic adenosine monophosphate response element binding protein 1; CTGF, connective tissue growth factor; ECM2, extracellular matrix protein 2; EGR1, early growth response protein 1; IGFBP7, insulin-like growth factor–binding protein 7; MAPK8IP3, mitogen-activated protein kinase 8 interacting protein 3; MAPKAPK5, mitogen-activated protein kinase–activated protein kinase 5; P4HA1, prolyl 4-hydroxylase subunit alpha-1; PKN1, protein kinase novel 1; PRKAG1, protein kinase adenosine monophosphate–activated noncatalytic subunit gamma 1; PGDFβ, platelet-derived growth factor-β; RHOA, Ras homolog gene family member G; RHOG, homolog gene family member G; SOX4, (sex determining region Y)-box 4; STK3, serine/threonine kinase 3; VEH, vehicle.

Significant effects (p < .05).