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Generation of inducible Tregs (iTregs) is not impaired in the absence of CCL25. A, Data represent the percentage of CD4+ Foxp3-positive iTregs in SPL, mLN, and cLP of Rag1−/− and Rag1−/−Ccl25−/− mice 8 weeks after transfer of naive CD4+ T cells. Data show 1 representative experiment out of 5. B, Mean ± SD percentages of CD4+ T cells that are Foxp3+ pooled from 3 independent experiments. NS, not significant.
