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. Author manuscript; available in PMC: 2018 Nov 22.
Published in final edited form as: Inflamm Bowel Dis. 2014 Jul;20(7):1165–1176. doi: 10.1097/MIB.0000000000000059

FIGURE 7.

FIGURE 7.

Distribution of proinflammatory and anti-inflammatory colonic macrophages is independent of CCL25/CCR9 interactions. A, Flow cytometry gating strategy used to investigate proinflammatory and anti-inflammatory macrophages. B and D, Representative dot plot of proinflammatory and anti-inflammatory macrophages in cLP of DSS-treated WT and Ccr9−/− mice (B) and Rag1−/− and Rag1−/−xCcl25−/− recipient mice transferred with WT CD45RBhi CD4+ T cells (D). Indicated percentages are relative to gated Gr-1loCD11bhiCD11cloSSClo leukocytes. C and E, Frequencies of proinflammatory and anti-inflammatory intestinal macrophages in DSS-treated WT and Ccr9−/− mice (C) and Rag1−/− and Rag1−/−xCcl25−/− mice transferred with WT CD45RBhi CD4+ T cells (E). Pooled data from 5 (B) and 3 experiments (D) (mean ± SD). Data represent 5 pooled experiments. NS, not significant.