Table 2.

Effect of Rutin treatment against cisplatin induced DNA damage in adult male rats

Groups (n = 4)	Control	Cisplatin	Cisplatin + Rutin	Rutin
No.of Comets/120 Cells	27 ± 2.97	58 ± 3.91a***	43 ± 1.10ab*	29 ± 1.41c*
Head length (μm)	158.71 ± 6.43	119.80 ± 3.87a***	132.29 ± 2.37a*	153.19 ± 7.42
Tail length (μm)	30.64 ± 1.91	53.25 ± 3.79a***	40.25 ± 1.27b*	33.74 ± 2.47c*
DNA in head (%)	88.80 ± 1.59	71.52 ± 2.87a***	74.37 ± 3.61a*	84.22 ± 1.77
DNA in tail (%)	10.84 ± 3.20	24.57 ± 1.88a***	22.51 ± 2.18a*	12.65 ± 1.12c*
Tail moment (μm)	3.60 ± 0.52	11.79 ± 1.59a***	6.95 ± 1.76ab*	3.84 ± 0.46c*

Values are expressed as mean ± SEM *p < 0.05, **p < 0.01, ***p < 0.001, ^a = Value vs control, ^b = Value vs cisplatin, ^c = Value vs Cisplatin+Rutin