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. 2018 Nov 21;18:107. doi: 10.1186/s12894-018-0421-9

Table 4.

Effect of Rutin treatment against cisplatin induced alterations on germ cell stages in adult male rats

Groups (n = 4) Spermatogonia Primary Spermatocytes Secondary Spermatocytes Spermatids
Control 61.85 ± 1.14 45.05 ± 1.09 43.55 ± 1.01 91.25 ± 1.07
Cisplatin 47.8 ± 1.14a*** 34.35 ± 1.04a*** 29.9 ± 1.09a*** 68 ± 1.57a***
Cisplatin+Rutin 55.85 ± 0.79b*** 39.1 ± 0.83ab** 37.75 ± 0.81a***b* 73.75 ± 1.63a***
Rutin 56.3 ± 1.40 40.3 ± 0.87a** 35.3 ± 1.00 78.7 ± 2.19a***

Values are expressed as mean ± SEM,*p < 0.05, **p < 0.01, ***p < 0.001, a = Value vs control, b = Value vs cisplatin, c = Value vs Cisplatin+Rutin