Table 1.
Cohort 1 comprising all respiratory tract isolates (n = 177). The distribution of clinical and laboratory characteristics per study year
| Culture year | 2010 | 2011 | 2012 | Total |
|---|---|---|---|---|
| Number of isolates | 43 | 52 | 82 | 177 |
| igaA1, n (%) | 31 (72%) | 39 (75%) | 51 (62%) | 121 (68%) |
| igaA1 alone, n (%) | 14 (33%) | 29 (56%) | 20 (24%) | 63 (36%) |
| igaA2a, n (%) | 12 (28%) | 13 (25%) | 30 (37%) | 55 (31%) |
| igaB1a, n (%) | 23 (53%) | 15 (29%) | 43 (52%) | 81 (46%) |
| igaB2, n (%) | 0 | 0 | 1 (1.2%) | 1 (0.6%) |
| Age (years), mean (median) | 24 (6) | 32 (36) | 29 (34) | 29 (32) |
| Gender, % female | 53% | 67% | 55% | 58% |
| Primary care referrals, n (%) | 31 (72%) | 33 (63%) | 55 (67%) | 119 (67%) |
| Acute otitis media, n (%) | 10 (24%) | 8 (15%) | 15 (18%) | 33 (19%) |
| Sinusitis, n (%) | 5 (12%) | 5 (10%) | 11 (13%) | 21 (12%) |
| Upper respiratory tract infection, n (%) | 17 (41%) | 21 (40%) | 18 (22%) | 56 (32%) |
| Lower respiratory tract infection, n (%) | 7 (17%) | 8 (15%) | 12 (15%) | 27 (15%) |
| Unclear diagnosis from referral, n (%) | 2 (5%) | 10 (19%) | 26 (32%) | 38 (22%) |
aSome isolates have both the igaA and igaB gene, resulting in a total percentage of > 100%