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. 2018 Nov 22;18:592. doi: 10.1186/s12879-018-3464-3

Table 3.

The iga protease gene variants among respiratory tract isolates with different properties

iga genotype igaA1 alone igaA2 igaB gene present p-value
Age (continuous, year), mean (median) 29.4 (21) 18.1 (4) 33.5 (40) < 0.001
Age category (n = 175, 2 missing) 0.042
  > 70 years, n (% within genotype) 5 (8%) 5 (6%)
 50–70 years, n (% within genotype) 14 (22%) 7 (13%) 20 (25%)
 20–50 years, n (% within genotype) 15 (24%) 14 (25%) 27 (34%)
 6–20 years, n (% within genotype) 5 (8%) 3 (5%) 6 (8%)
  < 6 years, n (% within genotype) 24 (38%) 31 (56%) 21 (27%)
Gender, % female 56% 53% 62% 0.684
Primary care referrals, % 71% 65% 64% 0.966
Clinical diagnosis (n = 175, 2 missing) 0.172
 AOM, n (% within genotype) 11 (17%) 13 (24%) 13 (16%)
 Sinusitis, n (% within genotype) 6 (10%) 6 (11%) 10 (13%)
 Upper respiratory tract infection, n (% within genotype) 26 (41%) 16 (29%) 24 (30%)
 Lower respiratory tract infection, n (% within genotype) 11 (17%) 3 (5%) 16 (20%)
 Unclear from referral, n (% within genotype) 9 (14%) 17 (31%) 16 (20%)

The Kruskal-Wallis test for continuous variables and the chi-2 test for categorical variables were used. Significant p-values are indicated in bold