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. 2018 Nov 21;18:107. doi: 10.1186/s12911-018-0665-z

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — A Variant Information System (VIS) integrates public data sources and makes their joint information available for use both within inhouse systems for patient knowledge management and directly to domain expert users. (Clipart source: openclipart.org; public domain)