Fig. 3.

Schematic representation of acetamiprid detection. Schematic representation of the reversible inhibition of the nanozyme activity of GNPs using an acetamiprid-specific S-18 ssDNA aptamer. Step A shows intrinsic peroxidase-like activity of GNPs that gets inhibited after shielding of the GNP surface through conjugation of S-18 aptamer molecules (step B). In the presence of acetamiprid target, the aptamer undergoes target-responsive structural changes and forms a supramolecular complex with acetamiprid resulting in free GNP to resume its peroxidase like activity (step C)

(Reprinted with permission from Weerathunge et al. [95]. Copyright 2014 American Chemical Society)