Table 2.
Effect of increased misclassification of stroke type at trial entry on ENOS primary analysis.
| Source of diagnosis of stroke type at trial entry | Results from regression model comparing effect of GTN versus no GTN |
|
|---|---|---|
| Log OR | SE log OR | |
| Central adjudication | −0.02473 | 0.05565 |
| SX3 | −0.02446 | 0.05563 |
| SX5 | −0.02426 | 0.05563 |
| SX10 | −0.02426 | 0.05561 |
| SX15 | −0.02411 | 0.05561 |
| SX20 | −0.02415 | 0.05561 |
SX3-SX20 refer to the misclassified Local clinical diagnoses. Kappa statistics showing the agreement between each diagnosis and Central adjudication diagnosis are 0.78, 0.67, 0.46, 0.32 and 0.21 for SX3-SX20 respectively.