Table 7.
Multivariate analysis of factors associated with NSN involvement in patients treated by radiotherapy and without chemotherapy prior to ALND
| Effect | P value | Contrast | Odd Ratio Estimate |
95% CI | P value |
|---|---|---|---|---|---|
| Age in class | 0.2626 | 41–75 vs > 75 | 1.402 | [0.409; 4.805] | 0.5905 |
| <=40 vs > 75 | 0.256 | [0.023; 2.887] | 0.2702 | ||
| Tumor Size | 0.9233 | 10–30 vs < =10 | 0.842 | [0.273; 2.598] | 0.7644 |
| > 30 vs < =10 | 0.982 | [0.226; 4.263] | 0.9807 | ||
| LVI | 0.3089 | Pos. Vs Neg. | 0.682 | [0.326; 1.425] | 0.3089 |
| Capsular Effraction | 0.0381 | Yes vs No | 2.357 | [1.048; 5.302] | 0.0381 |
| Hormonal receptors | 0.4821 | Pos. Vs Neg. | 1.647 | [0.410; 6.617] | 0.4821 |
| HER2 Status | 0.1906 | Pos. Vs Neg. | 0.376 | [0.087; 1.626] | 0.1906 |
| Histology Type | 0.5892 | Mixed/Other vs lobular | 0.478 | [0.111; 2.047] | 0.3196 |
| Ductal vs lobular | 0.665 | [0.243; 1.818] | 0.4267 | ||
| SBR Grade | 0.0650 | Gr II vs Gr I | 3.332 | [1.214; 9.143] | 0.0195 |
| Gr III vs Gr I | 2.714 | [0.831; 8.862] | 0.0982 | ||
| Nb Involved SN | 0.1171 | > 2 vs < =2 | 6.797 | [0.618; 74.708] | 0.1171 |
| SN Status | 0.3734 | Macro vs ITC | 3.737 | [0.451; 30.991] | 0.2219 |
| Micro vs ITC | 2.635 | [0.305; 22.767] | 0.3784 |
Abbreviations: CI confidence interval