Figure 5. Ewald sphere correction (A) FSC curves between independently refined half-maps without Ewald sphere correction (grey); with Ewald sphere correction with the correct curvature (green) and with Ewald sphere correction with the inverse curvature (orange).

(B) As in A, but FSC curves are between the cryo-EM and the corresponding atomic model (PDB-5UU5) (Hryc et al., 2017). (C) Representative density features without Ewald sphere correction (grey) with Ewald sphere correction and the correct curvature (green) and with Ewald sphere correction and the reverse curvature (orange).