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. 2018 Nov 9;97(45):e13120. doi: 10.1097/MD.0000000000013120

Figure 7.

Figure 7

M72-specific CD4+ T-cell responses following vaccination with M72/AS01E according to Interferon Gamma Release Assay results at baseline. Data for IGRA-positive and IGRA-negative participants vaccinated with M72/AS01E and included in the ATP cohort are presented as percentages of M72-specific CD4+ T-cells expressing at least 2 immune markers among IFN-γ, IL-2, TNF-α, and CD40L of all CD4+ T-cells, along with first and third quartiles and minimum and maximum values measured. % = percentage; ATP = according-to-protocol; D7 = 7 days post-dose 1; D30 = 30 days post-dose 1; D37 = 7 days post-dose 2; D60 = 30 days post-dose 2; HIV+ART+ = HIV-positive participants on antiretroviral therapy; HIV+ART- = HIV-positive, antiretroviral therapy-naïve participants; HIV− = HIV-negative participants; IGRA = interferon-gamma release assay; M7 = 6 months post-dose 2; Pre = pre-vaccination; Q1 = first quartile; Q3 = third quartile; Y1 = 1 year post-dose 2; Y2 = 2 years post-dose 2; Y3 = 3 years post-dose 2.