Table 2.

Peak vasoactive medication dosing in first 24 h

Vasoactive medication	Total cohort (n = 5352)	Derivation cohort (n = 4033)	Validation cohort (n = 1319)	p
Vasopressin
Total patients	2200 (41.1)	1644 (40.8)	556 (42.2)	0.38
Peak dose (U/min)	0.04 (0.04–0.04)	0.04 (0.04–0.04)	0.04 (0.04–0.04)	0.98
Epinephrine
Total patients	1633 (30.5)	1207 (29.9)	426 (32.3)	0.11
Peak dose (mcg/kg/min)	0.05 (0.04–0.1)	0.05 (0.04–0.1)	0.05 (0.04–0.1)	0.47
Phenylephrine
Total patients	355 (6.6)	280 (6.9)	75 (5.7)	0.13
Peak dose (mcg/kg/min)	0.6 (0.1–1.3)	0.6 (0.3–1.2)	0.8 (0.4–1.4)	0.10
Dobutamine
Total patients	271 (5.1)	201 (5.0)	70 (5.3)	0.66
Peak dose (mcg/kg/min)	5 (5–10)	5 (5–10)	5 (5–7.5)	0.38
Dopamine
Total patients	208 (3.9)	150 (3.7)	58 (4.4)	0.29
Peak dose (mcg/kg/min)	5 (3–10)	5 (3–10)	5 (3–13)	0.29
Milrinone
Total patients	700 (13.1)	522 (12.9)	178 (13.5)	0.61
Peak dose (mcg/kg/min)	0.25 (0.25–0.37)	0.25 (0.25–0.38)	0.25 (0.2–0.3)	0.12

Total (percentage) or median (interquartile range)