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. 2018 Nov 14;15(6):711–719. doi: 10.1007/s13770-018-0166-2

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© The Korean Tissue Engineering and Regenerative Medicine Society and Springer Science+Business Media B.V., part of Springer Nature 2018

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Fig. 1 — A Effect of CTGF siRNA/MPG^ΔNLS ratio (1:1–1:24) on down-regulation of CTGF in fibroblast wound model: mismatch siRNA was served as a negative control and Lipofectamine was served as a positive control. CTGFsiRNA/MPG^ΔNLS showed no significant silencing effect on CTGF level. B Effect of CTGF siRNA/KALA ratio (1:1–1:24) on down-regulation of CTGF expression in fibroblast wound model. CTGFsiRNA/KALA showed 40–60% down-regulation of CTGF at 1:12 and 1:24 ratios. (*denotes statistically different from control, p < 0.01)